NFATC4 antibody (AA 560-710)

Catalog No. ABIN7268979

This anti-NFATC4 antibody is a Rabbit Polyclonal antibody detecting NFATC4 in WB. Suitable for Human.

Quick Overview for NFATC4 antibody (AA 560-710) (ABIN7268979)

Target: NFATC4 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 4 (NFATC4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFATC4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NFATC4 Antibody

Binding Specificity: AA 560-710

Purpose: NFATC4 Rabbit pAb

Sequence: QGGGKVVSVQ AASVPIECSQ RSAQELPQVE AYSPSACSVR GGEELVLTGS NFLPDSKVVF IERGPDGKLQ WEEEATVNRL QSNEVTLTLT VPEYSNKRVS RPVQVYFYVS NGRRKRSPTQ SFRFLPVICK EEPLPDSSLR GFPSASATPF G

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 560-710 of human NFATC4 (NP_004545.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NFATC4

Target: NFATC4 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 4 (NFATC4))

Alternative Name: NFATC4

Background: This gene encodes a member of the nuclear factor of activated T cells (NFAT) protein family. The encoded protein is part of a DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor stimulation and an inducible nuclear component. NFAT proteins are activated by the calmodulin-dependent phosphatase, calcineurin. The encoded protein plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of interleukin-2 and interleukin-4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],NF-AT3,NF-ATC4,NFAT3,NFATC4,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,NFATC4

Gene ID: 4776

UniProt: Q14934

Pathways: RTK Signaling, WNT Signaling