OSBPL2 antibody (AA 291-480)

Catalog No. ABIN7269137

The Rabbit Polyclonal anti-OSBPL2 antibody has been validated for WB. It is suitable to detect OSBPL2 in samples from Human.

Quick Overview for OSBPL2 antibody (AA 291-480) (ABIN7269137)

Target: OSBPL2 (Oxysterol Binding Protein-Like 2 (OSBPL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OSBPL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-OSBPL2 Antibody

Binding Specificity: AA 291-480

Purpose: OSBPL2 Rabbit pAb

Sequence: NKKKLFMIYG KWTECLWGID PVSYESFKKQ ERRGDHLRKA KLDEDSGKAD SDVADDVPVA QETVQVIPGS KLLWRINTRP PNSAQMYNFT SFTVSLNELE TGMEKTLPPT DCRLRPDIRG MENGNMDLAS QEKERLEEKQ REARRERAKE EAEWQTRWFY PGNNPYTGTP DWLYAGDYFE RNFSDCPDIY

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 291-480 of human OSBPL2 (NP_653081.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for OSBPL2

Target: OSBPL2 (Oxysterol Binding Protein-Like 2 (OSBPL2))

Alternative Name: OSBPL2

Background: This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although the encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.,OSBPL2,DFNA67,DNFA67,ORP-2,ORP2,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Cardiovascular,Lipids,OSBPL2

Molecular Weight: 53kDa/55kDa

Gene ID: 9885

UniProt: Q9H1P3