This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target
POR
(P450 (Cytochrome) Oxidoreductase (POR))
Alternative Name
POR
Background
This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. [provided by RefSeq, Jul 2008],CPR, CYPOR, P450R,Cancer,Cardiovascular,Drug metabolism,Endocrine & Metabolism,Lipid Metabolism,Lipid Metabolism_Cytochromes,Lipid Metabolism_Lipases,Lipids,Mitochondrial metabolism,Mitochondrial metabolism_Cytochromes,Signal Transduction,POR