PON3 antibody (AA 250-350)

Catalog No. ABIN7269174

The Rabbit Polyclonal anti-PON3 antibody (ABIN7269174) specifically detects PON3 in WB. The antibody is reactive with Human samples.

Quick Overview for PON3 antibody (AA 250-350) (ABIN7269174)

Target: PON3 (Paraoxonase 3 (PON3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PON3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PON3 Antibody

Binding Specificity: AA 250-350

Purpose: PON3 Rabbit pAb

Sequence: HDNWDLTQLK VIQLGTLVDN LTVDPATGDI LAGCHPNPMK LLNYNPEDPP GSEVLRIQNV LSEKPRVSTV YANNGSVLQG TSVASVYHGK ILIGTVFHKT L

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 250-350 of human PON3 (NP_000931.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PON3

Target: PON3 (Paraoxonase 3 (PON3))

Alternative Name: PON3

Background: This gene is a member of the paraoxonase family and lies in a cluster on chromosome 7 with the other two family members. The encoded protein is secreted into the bloodstream and associates with high-density lipoprotein (HDL). The protein also rapidly hydrolyzes lactones and can inhibit the oxidation of low-density lipoprotein (LDL), a function that is believed to slow the initiation and progression of atherosclerosis. Alternatively spliced variants which encode different protein isoforms have been described, however, only one has been fully characterized.,PON3,Cancer,Signal Transduction,Endocrine & Metabolism,Drug metabolism,Neuroscience,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,Cardiovascular,Lipids,Lipoproteins/Apolipoproteins,PON3

Molecular Weight: 39kDa

Gene ID: 5446

UniProt: Q15166

Pathways: Monocarboxylic Acid Catabolic Process