PCM1 antibody (AA 1-260)

Catalog No. ABIN7269217

This Rabbit Polyclonal antibody specifically detects PCM1 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for PCM1 antibody (AA 1-260) (ABIN7269217)

Target: PCM1 (Pericentriolar Material 1 (PCM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-PCM1 Antibody

Binding Specificity: AA 1-260

Purpose: PCM1 Rabbit pAb

Sequence: MATGGGPFED GMNDQDLPNW SNENVDDRLN NMDWGAQQKK ANRSSEKNKK KFGVESDKRV TNDISPESSP GVGRRRTKTP HTFPHSRYMS QMSVPEQAEL EKLKQRINFS DLDQRSIGSD SQGRATAANN KRQLSENRKP FNFLPMQINT NKSKDASTSP PNRETIGSAQ CKELFASALS NDLLQNCQVS EEDGRGEPAM ESSQIVSRLV QIRDYITKAS SMREDLVEKN ERSANVERLT HLIDHLKEQE KSYMKFLKKI

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PCM1 (NP_006188.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PCM1

Target: PCM1 (Pericentriolar Material 1 (PCM1))

Alternative Name: PCM1

Background: The protein encoded by this gene is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene.,PCM1,PTC4,RET/PCM-1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,PCM1

Molecular Weight: 59kDa/222kDa/228kDa

Gene ID: 5108

UniProt: Q15154

Pathways: Stem Cell Maintenance, M Phase, Maintenance of Protein Location