PDE4A antibody

Catalog No. ABIN7269302

The Rabbit Polyclonal anti-PDE4A antibody has been validated for WB, IHC and IF. It is suitable to detect PDE4A in samples from Human.

Quick Overview for PDE4A antibody (ABIN7269302)

Target: PDE4A (phosphodiesterase 4A, CAMP-Specific (PDE4A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE4A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PDE4A Antibody

Purpose: PDE4A Rabbit pAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant protein of human PDE4A.

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PDE4A

Target: PDE4A (phosphodiesterase 4A, CAMP-Specific (PDE4A))

Alternative Name: PDE4A

Background: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.,PDE4, DPDE2, PDE46,PDE4A

Molecular Weight: 378kDa

Gene ID: 5141

UniProt: P27815

Pathways: cAMP Metabolic Process