PDE6G antibody (AA 1-87)

Catalog No. ABIN7269304

This Rabbit Polyclonal antibody specifically detects PDE6G in WB and IF. It exhibits reactivity toward Human.

Quick Overview for PDE6G antibody (AA 1-87) (ABIN7269304)

Target: PDE6G (phosphodiesterase 6G, CGMP-Specific, Rod, gamma (PDE6G))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE6G antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-PDE6G Antibody

Binding Specificity: AA 1-87

Purpose: PDE6G Rabbit pAb

Sequence: MNLEPPKAEF RSATRVAGGP VTPRKGPPKF KQRQTRQFKS KPPKKGVQGF GDDIPGMEGL GTDITVICPW EAFNHLELHE LAQYGII

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-87 of human PDE6G (NP_002593.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PDE6G

Target: PDE6G (phosphodiesterase 6G, CGMP-Specific, Rod, gamma (PDE6G))

Alternative Name: PDE6G

Background: This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009],PDEG,RP57,PDE6G,Signal Transduction,PDE6G

Gene ID: 5148

UniProt: P18545

Pathways: EGFR Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction