PHC2 antibody (AA 250-323)

Catalog No. ABIN7269454

This Rabbit Polyclonal antibody specifically detects PHC2 in WB. It exhibits reactivity toward Human.

Quick Overview for PHC2 antibody (AA 250-323) (ABIN7269454)

Target: PHC2 (PhC2) (Polyhomeotic Homolog 2 (Drosophila) (PhC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHC2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PHC2 Antibody

Binding Specificity: AA 250-323

Purpose: PHC2 Rabbit pAb

Sequence: HFLPSEPTKW NVEDVYEFIR SLPGCQEIAE EFRAQEIDGQ ALLLLKEDHL MSAMNIKLGP ALKIYARISM LKDS

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 250-323 of human PHC2 (NP_004418.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PHC2

Target: PHC2 (PhC2) (Polyhomeotic Homolog 2 (Drosophila) (PhC2))

Alternative Name: PHC2

Background: In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.,PHC2,EDR2,HPH2,PH2,Epigenetics & Nuclear Signaling,Chromatin Remodeling,PHC2

Molecular Weight: 30kDa/35kDa/87kDa/90kDa

Gene ID: 1912

UniProt: Q8IXK0