POF1B antibody (AA 330-560)

Catalog No. ABIN7269509

The Rabbit Polyclonal anti-POF1B antibody has been validated for WB. It is suitable to detect POF1B in samples from Human.

Quick Overview for POF1B antibody (AA 330-560) (ABIN7269509)

Target: POF1B (Premature Ovarian Failure, 1B (POF1B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POF1B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-POF1B Antibody

Binding Specificity: AA 330-560

Purpose: POF1B Rabbit pAb

Sequence: LVLSTFSNIR EELGHLQNDM TSLENDKMRL EKDLSFKDTQ LKEYEELLAS VRANNHQQQQ GLQDSSSKCQ ALEENNLSLR HTLSDMEYRL KELEYCKRNL EQENQNLRMQ VSETCTGPML QAKMDEIGNH YTEMVKNLRM EKDREICRLR SQLNQYHKDV SKREGSCSDF QFKLHELTSL LEEKDSLIKR QSEELSKLRQ EIYSSHNQPS TGGRTTITTK KYRTQYPILG L

Cross-Reactivity: Human, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 330-560 of human POF1B (NP_079197.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for POF1B

Target: POF1B (Premature Ovarian Failure, 1B (POF1B))

Alternative Name: POF1B

Background: Premature ovarian failure (POF) is characterized by primary or secondary amenorrhea in women less than 40 years old. Two POF susceptibility regions called "POF1" and "POF2" have been identified by breakpoint mapping of X-autosome translocations. POF1 extends from Xq21-qter while POF2 extends from Xq13.3 to Xq21.1. This gene, POF1B, resides in the POF2 region. This gene is expressed at trace levels in mouse prenatal ovary and is barely detectable or absent from adult ovary, in human and in the mouse respectively. This gene's expression is restricted to epithelia with its highest expression in the epidermis, and oro-pharyngeal and gastro-intestinal tracts. The protein encoded by this gene binds non-muscle actin filaments. The role this gene may play in the etiology of premature ovarian failure remains to be determined. [provided by RefSeq, Jan 2010],POF;POF2B;POF1B,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Tight Junctions,Cytoskeleton,Microfilaments,POF1B

Gene ID: 79983

UniProt: Q8WVV4