CA8 antibody (AA 161-260) (Biotin)

Catalog No. ABIN717448

This Rabbit Polyclonal antibody specifically detects CA8 in ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for CA8 antibody (AA 161-260) (Biotin) (ABIN717448)

Target: CA8 (Carbonic Anhydrase VIII (CA8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CA8 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CA8 Antibody (Biotin)

Binding Specificity: AA 161-260

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CA8

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CA8

Target: CA8 (Carbonic Anhydrase VIII (CA8))

Alternative Name: CA8

Background:

Synonyms: CA 12, CA VIII, CA-VIII, Ca8, CAH8_HUMAN, CALS, Carbonic anhydrase related protein, Carbonic anhydrase VIII, Carbonic anhydrase-related protein, CARP, MGC120502, MGC99509.

Background: The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form.

Gene ID: 767