PPP1R12B antibody (AA 660-930)

Catalog No. ABIN7269677

The Rabbit Polyclonal anti-PPP1R12B antibody has been validated for WB. It is suitable to detect PPP1R12B in samples from Human.

Quick Overview for PPP1R12B antibody (AA 660-930) (ABIN7269677)

Target: PPP1R12B (Protein Phosphatase 1, Regulatory Subunit 12B (PPP1R12B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R12B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PPP1R12B Antibody

Binding Specificity: AA 660-930

Purpose: PPP1R12B Rabbit pAb

Sequence: TFSRSRAERQ AQEQPREKPT DTEGLEGSPE KHEPSAVPAT EAGEGQQPWG RSLDEEPICH RLRCPAQPDK PTTPASPSTS RPSLYTSSHL LWTNRFSVPD SESSETTTNT TTAKEMDKNE NEEADLDEQS SKRLSIRERR RPKERRRGTG INFWTKDEDE TDGSEEVKET WHERLSRLES GGSNPTTSDS YGDRASARAR REAREARLAT LTSRVEEDSN RDYKKLYESA LTENQKLKTK LQEAQLELAD IKSKLEKVAQ QKQEKTSDRS S

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 660-930 of human PPP1R12B (NP_002472.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PPP1R12B

Target: PPP1R12B (Protein Phosphatase 1, Regulatory Subunit 12B (PPP1R12B))

Alternative Name: PPP1R12B

Background: Myosin phosphatase is a protein complex comprised of three subunits: a catalytic subunit (PP1c-delta, protein phosphatase 1, catalytic subunit delta), a large regulatory subunit (MYPT, myosin phosphatase target) and small regulatory subunit (sm-M20). Two isoforms of MYPT have been isolated--MYPT1 and MYPT2, the first of which is widely expressed, and the second of which may be specific to heart, skeletal muscle, and brain. Each of the MYPT isoforms functions to bind PP1c-delta and increase phosphatase activity. This locus encodes both MYTP2 and M20. Alternatively spliced transcript variants encoding different isoforms have been identified. Related pseudogenes have been defined on the Y chromosome. [provided by RefSeq, Oct 2011],MYPT2,PP1bp55,PPP1R12B,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Motor Proteins,PPP1R12B

Gene ID: 4660

UniProt: O60237

Pathways: M Phase