Proteoglycan 4 antibody (AA 1264-1363)

Catalog No. ABIN7269722

The Rabbit Polyclonal anti-Proteoglycan 4 antibody has been validated for WB. It is suitable to detect Proteoglycan 4 in samples from Human.

Quick Overview for Proteoglycan 4 antibody (AA 1264-1363) (ABIN7269722)

Target: Proteoglycan 4 (PRG4)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Proteoglycan 4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Proteoglycan 4 Antibody

Binding Specificity: AA 1264-1363

Purpose: PRG4 Rabbit pAb

Sequence: ERAIGPSQTH TIRIQYSPAR LAYQDKGVLH NEVKVSILWR GLPNVVTSAI SLPNIRKPDG YDYYAFSKDQ YYNIDVPSRT ARAITTRSGQ TLSKVWYNCP

Cross-Reactivity: Human, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1264-1363 of human PRG4 (NP_001121180.2).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Proteoglycan 4

Target: Proteoglycan 4 (PRG4)

Alternative Name: PRG4

Background: The protein encoded by this gene is a large proteoglycan that is synthesized by chondrocytes located at the surface of articular cartilage and by some synovial lining cells. This protein contains both chondroitin sulfate and keratan sulfate glycosaminoglycans. It functions as a boundary lubricant at the cartilage surface and contributes to the elastic absorption and energy dissipation of synovial fluid. Mutations in this gene result in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Alternative splicing results in multiple transcript variants.,PRG4,CACP,HAPO,JCAP,MSF,SZP,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Bone,PRG4

Molecular Weight: 102kDa/136kDa/141kDa/146kDa/151kDa

Gene ID: 10216

UniProt: Q92954