PLP1 antibody (AA 145-210)

Catalog No. ABIN7269724

This Rabbit Polyclonal antibody specifically detects PLP1 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for PLP1 antibody (AA 145-210) (ABIN7269724)

Target: PLP1 (Proteolipid Protein 1 (PLP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PLP1 Antibody

Binding Specificity: AA 145-210

Purpose: PLP1 Rabbit pAb

Sequence: TWTTCQSIAF PSKTSASIGS LCADARMYGV LPWNAFPGKV CGSNLLSICK TAEFQMTFHL FIAAFV

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 145-210 of human PLP1 (NP_955772.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PLP1

Target: PLP1 (Proteolipid Protein 1 (PLP1))

Alternative Name: PLP1

Background: This gene encodes a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively splicing results in multiple transcript variants, including the DM20 splice variant.,PLP1,GPM6C,HLD1,MMPL,PLP,PLP/DM20,PMD,SPG2,Cell Biology & Developmental Biology,Cell Adhesion,Neuroscience,Cell Type Marker,Oligodendrocyte marker,PLP1

Molecular Weight: 26kDa/30kDa

Gene ID: 5354

UniProt: P60201