PCDHA10 antibody (AA 130-210)

Catalog No. ABIN7269733

This Rabbit Polyclonal antibody specifically detects PCDHA10 in WB. It exhibits reactivity toward Human.

Quick Overview for PCDHA10 antibody (AA 130-210) (ABIN7269733)

Target: PCDHA10 (Protocadherin alpha 10 (PCDHA10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHA10 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PCDHA10 Antibody

Binding Specificity: AA 130-210

Purpose: PCDHA10 Rabbit pAb

Sequence: PRFSVTEQKL SIPESRLLDS RFPLEGASDA DVGENALLTY KLSPNEYFVL DIINKKDKDK FPVLVLRKLL DREENPQLKL L

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 130-210 of human PCDHA10 (NP_114066.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PCDHA10

Target: PCDHA10 (Protocadherin alpha 10 (PCDHA10))

Alternative Name: PCDHA10

Background: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.,PCDHA10,CNR8,CNRN8,CNRS8,CRNR8,PCDH-ALPHA10,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cell Adhesion,Cadherins,Cytoskeleton,Neuroscience,PCDHA10

Gene ID: 56139

UniProt: Q9Y5I2