PCDHb4 antibody (AA 28-300)

Catalog No. ABIN7269735

This anti-PCDHb4 antibody is a Rabbit Polyclonal antibody detecting PCDHb4 in WB and IF. Suitable for Human.

Quick Overview for PCDHb4 antibody (AA 28-300) (ABIN7269735)

Target: PCDHb4 (Protocadherin beta 4 (PCDHb4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHb4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-PCDHb4 Antibody

Binding Specificity: AA 28-300

Purpose: PCDHB4 Rabbit pAb

Sequence: EPIRYSVLEE TESGSFVAHL AKDLGLGIGE LASRSARVLS DDDKQRLQLD RQTGDLLLRE KLDREELCGP IEPCVLHFQV FLEMPVQFFQ GELLIQDIND HSPIFPEREV LLKILENSQP GTLFPLLIAE DLDVGSNGLQ KYTISPNSHF HILTRNHSEG KKYPDLVQDK PLDREEQPEF SLTLVALDGG SPPRSGTVMV RILIMDINDN APEFVHTPYG VQVLENSPLD SPIVRVLARD IDAGNFGSVS YGLFQASDEI KQTFSINEVT GEI

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 28-300 of human PCDHB4 (NP_061761.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PCDHb4

Target: PCDHb4 (Protocadherin beta 4 (PCDHb4))

Alternative Name: PCDHB4

Background: This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. [provided by RefSeq, Jul 2008],PCDH-BETA4;PCDHB4,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cadherins,Cytoskeleton,Neuroscience,Calcium Signaling,PCDHB4

Gene ID: 56131

UniProt: Q9Y5E5