PUS7 antibody (AA 352-661)

Catalog No. ABIN7269739

This Rabbit Polyclonal antibody specifically detects PUS7 in WB. It exhibits reactivity toward Human.

Quick Overview for PUS7 antibody (AA 352-661) (ABIN7269739)

Target: PUS7 (Pseudouridylate Synthase 7 Homolog (PUS7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PUS7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PUS7 Antibody

Binding Specificity: AA 352-661

Purpose: PUS7 Rabbit pAb

Sequence: ITGTDDQVQQ AMNSLKEIGF INYYGMQRFG TTAVPTYQVG RAILQNSWTE VMDLILKPRS GAEKGYLVKC REEWAKTKDP TAALRKLPVK RCVEGQLLRG LSKYGMKNIV SAFGIIPRNN RLMYIHSYQS YVWNNMVSKR IEDYGLKPVP GDLVLKGATA TYIEEDDVNN YSIHDVVMPL PGFDVIYPKH KIQEAYREML TADNLDIDNM RHKIRDYSLS GAYRKIIIRP QNVSWEVVAY DDPKIPLFNT DVDNLEGKTP PVFASEGKYR ALKMDFSLPP STYATMAIRE VLKMDTSIKN QTQLNTTWLR

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 352-661 of human PUS7 (NP_061915.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PUS7

Target: PUS7 (Pseudouridylate Synthase 7 Homolog (PUS7))

Alternative Name: PUS7

Background: Pseudouridylate synthase that catalyzes pseudouridylation of RNAs. Acts as a regulator of protein synthesis in embryonic stem cells by mediating pseudouridylation of RNA fragments derived from tRNAs (tRFs: pseudouridylated tRFs inhibit translation by targeting the translation initiation complex. Also catalyzes pseudouridylation of mRNAs: mediates pseudouridylation of mRNAs with the consensus sequence 5'-UGUAG-3'. In addition to mRNAs and tRNAs, binds other types of RNAs, such as snRNAs, Y RNAs and vault RNAs, suggesting that it can catalyze pseudouridylation of many RNA types.,PUS7,Epigenetics & Nuclear Signaling,RNA Binding,PUS7

Gene ID: 54517

UniProt: Q96PZ0