Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

RANBP2 antibody

This anti-RANBP2 antibody is a Rabbit Polyclonal antibody detecting RANBP2 in WB and IHC. Suitable for Human.
Catalog No. ABIN7269843

Quick Overview for RANBP2 antibody (ABIN7269843)

Target

See all RANBP2 Antibodies
RANBP2 (RAN Binding Protein 2 (RANBP2))

Reactivity

  • 25
  • 19
  • 18
  • 1
Human

Host

  • 26
Rabbit

Clonality

  • 26
Polyclonal

Conjugate

  • 8
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This RANBP2 antibody is un-conjugated

Application

  • 13
  • 9
  • 6
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Purpose

    RANBP2 Rabbit pAb

    Cross-Reactivity

    Mouse, Rat

    Characteristics

    Polyclonal Antibodies

    Purification

    Affinity purification

    Immunogen

    Recombinant protein of human RANBP2.

    Isotype

    IgG
  • Application Notes

    WB,1:500 - 1:2000,IHC,1:50 - 1:200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    RANBP2 (RAN Binding Protein 2 (RANBP2))

    Alternative Name

    RANBP2

    Background

    RAN is a small GTP-binding protein of the RAS superfamily that is associated with the nuclear membrane and is thought to control a variety of cellular functions through its interactions with other proteins. This gene encodes a very large RAN-binding protein that immunolocalizes to the nuclear pore complex. The protein is a giant scaffold and mosaic cyclophilin-related nucleoporin implicated in the Ran-GTPase cycle. The encoded protein directly interacts with the E2 enzyme UBC9 and strongly enhances SUMO1 transfer from UBC9 to the SUMO1 target SP100. These findings place sumoylation at the cytoplasmic filaments of the nuclear pore complex and suggest that, for some substrates, modification and nuclear import are linked events. This gene is partially duplicated in a gene cluster that lies in a hot spot for recombination on chromosome 2q. [provided by RefSeq, Jul 2008],ADANE, ANE1, IIAE3, NUP358, TRP1, TRP2,Cell Biology & Developmental Biology,Cell Cycle,Epigenetics & Nuclear Signaling,Signal Transduction,Ubiquitin,RANBP2

    Gene ID

    5903

    UniProt

    P49792

    Pathways

    Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
You are here:
Chat with us!