RASAL1 antibody (AA 120-340)

Catalog No. ABIN7269873

This anti-RASAL1 antibody is a Rabbit Polyclonal antibody detecting RASAL1 in WB. Suitable for Human.

Quick Overview for RASAL1 antibody (AA 120-340) (ABIN7269873)

Target: RASAL1 (RAS Protein Activator Like 1 (GAP1 Like) (RASAL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASAL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RASAL1 Antibody

Binding Specificity: AA 120-340

Purpose: RASAL1 Rabbit pAb

Sequence: ICLSVQMLED GQGRCLRCHV LQARDLAPRD ISGTSDPFAR VFWGSQSLET STIKKTRFPH WDEVLELREM PGAPSPLRVE LWDWDMVGKN DFLGMVEFSP KTLQQKPPKG WFRLLPFPRA EEDSGGNLGA LRVKVRLIED RVLPSQCYQP LMELLMESVQ GPAEEDTASP LALLEELTLG DCRQDLATKL VKLFLGRGLA GRFLDYLTRR EVARTMDPNT L

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 120-340 of human RASAL1 (NP_004649.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RASAL1

Target: RASAL1 (RAS Protein Activator Like 1 (GAP1 Like) (RASAL1))

Alternative Name: RASAL1

Background: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described,RASAL1,RASAL,Cancer,Tumor suppressors,Signal Transduction,G protein signaling,Signal Transduction,RASAL1

Molecular Weight: 86kDa/90kDa

Gene ID: 8437

UniProt: O95294