Ras-Related C3 Botulinum Toxin Substrate 1 (RAC3A) (pSer71) antibody

Catalog No. ABIN7269877

This Rabbit Monoclonal antibody specifically detects Ras-Related C3 Botulinum Toxin Substrate 1 in WB. It exhibits reactivity toward Human.

Quick Overview for Ras-Related C3 Botulinum Toxin Substrate 1 (RAC3A) (pSer71) antibody (ABIN7269877)

Target: Ras-Related C3 Botulinum Toxin Substrate 1 (RAC3A)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Application: Western Blotting (WB)

Product Details

Binding Specificity: pSer71

Purpose: Phospho-Rac1/Cdc42-S71 Rabbit mAb

Cross-Reactivity: Human

Characteristics: Phosphorylated Antibodies

Purification: Affinity purification

Immunogen: A phospho specific peptide corresponding to residues surrounding S71 of human Rac1/Cdc42

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details

Target: Ras-Related C3 Botulinum Toxin Substrate 1 (RAC3A)

Alternative Name: CDC42/RAC1

Background: The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013],CDC42Hs, G25K, TKS,CDC42/RAC1

Molecular Weight: 24kDa

Gene ID: 998, 5879

UniProt: P60953, P63000