RASD1 antibody (AA 132-281)

Catalog No. ABIN7269879

Product Details anti-RASD1 Antibody

Target: RASD1 (RAS, Dexamethasone-Induced 1 (RASD1))

Binding Specificity: AA 132-281

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASD1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: RASD1 Rabbit pAb

Sequence: TKENVDVPLV ICGNKGDRDF YREVDQREIE QLVGDDPQRC AYFEISAKKN SSLDQMFRAL FAMAKLPSEM SPDLHRKVSV QYCDVLHKKA LRNKKLLRAG SGGGGGDPGD AFGIVAPFAR RPSVHSDLMY IREKASAGSQ AKDKERCVIS

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 132-281 of human RASD1 (NP_057168.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RASD1

Target: RASD1 (RAS, Dexamethasone-Induced 1 (RASD1))

Alternative Name: RASD1 (RASD1 Products)

Background: This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,RASD1,AGS1,DEXRAS1,MGC:26290,Signal Transduction,G protein signaling,Signal Transduction,RASD1

Molecular Weight: 13kDa/31kDa

Gene ID: 51655

UniProt: Q9Y272