FIP200 antibody (C-Term)

Catalog No. ABIN7269881

The Rabbit Polyclonal anti-FIP200 antibody has been validated for WB and IHC. It is suitable to detect FIP200 in samples from Human.

Quick Overview for FIP200 antibody (C-Term) (ABIN7269881)

Target: FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FIP200 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-FIP200 Antibody

Binding Specificity: C-Term

Purpose: FIP200 Rabbit pAb

Sequence: DFQVGDLVLI ILDERHDNYV LFTVSPTLYF LHSESLPALD LKPGEGASGA SRRPWVLGKV MEKEYCQAKK AQNRFKVPLG TKFYRVKAVS WNKKV

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1500 to the C-terminus of human FIP200 (NP_055596.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FIP200

Target: FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))

Alternative Name: RB1CC1

Background: The protein encoded by this gene interacts with signaling pathways to coordinately regulate cell growth, cell proliferation, apoptosis, autophagy, and cell migration. This tumor suppressor also enhances retinoblastoma 1 gene expression in cancer cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,RB1CC1,ATG17,CC1,FIP200,PPP1R131,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Autophagy,Endocrine & Metabolism,Mitochondrial metabolism,Endocrine and metabolic diseases,Diabetes,Regulators,RB1CC1

Molecular Weight: 182kDa/183kDa

Gene ID: 9821

UniProt: Q8TDY2

Pathways: Regulation of Cell Size, Autophagy