SGEF antibody (AA 592-871)

Catalog No. ABIN7269968

The Rabbit Polyclonal anti-SGEF antibody has been validated for WB, IHC and IF. It is suitable to detect SGEF in samples from Human.

Quick Overview for SGEF antibody (AA 592-871) (ABIN7269968)

Target: SGEF (ARHGEF26) (rho Guanine Nucleotide Exchange Factor (GEF) 26 (ARHGEF26))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGEF antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-SGEF Antibody

Binding Specificity: AA 592-871

Purpose: ARHGEF26 Rabbit pAb

Sequence: ICQKTPKDSP KYEVCKRALK EVSKLVRLCN EGARKMERTE MMYTINSQLE FKIKPFPLVS SSRWLVKRGE LTAYVEDTVL FSRRTSKQQV YFFLFNDVLI ITKKKSEESY NVNDYSLRDQ LLVESCDNEE LNSSPGKNSS TMLYSRQSSA SHLFTLTVLS NHANEKVEML LGAETQSERA RWITALGHSS GKPPADRTSL TQVEIVRSFT AKQPDELSLQ VADVVLIYQR VSDGWYEGER LRDGERGWFP MECAKEITCQ ATIDKNVERM GRLLGLETNV

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 592-871 of human ARHGEF26 (NP_056410.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SGEF

Target: SGEF (ARHGEF26) (rho Guanine Nucleotide Exchange Factor (GEF) 26 (ARHGEF26))

Alternative Name: ARHGEF26

Background: This gene encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. These proteins regulate Rho GTPases by catalyzing the exchange of GDP for GTP. The encoded protein specifically activates RhoG and plays a role in the promotion of macropinocytosis. Underexpression of the encoded protein may be a predictive marker of chemoresistant disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011],ARHGEF26,CSGEF,HMFN1864,SGEF,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Signal Transduction,ARHGEF26

Molecular Weight: 48kDa/88kDa/97kDa

Gene ID: 26084

UniProt: Q96DR7