SGEF antibody (N-Term)

Catalog No. ABIN2786132

This Rabbit Polyclonal antibody specifically detects SGEF in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Rabbit, Pig and Saccharomyces cerevisiae.

Quick Overview for SGEF antibody (N-Term) (ABIN2786132)

Target: SGEF (ARHGEF26) (rho Guanine Nucleotide Exchange Factor (GEF) 26 (ARHGEF26))

Reactivity: Human, Rat, Mouse, Cow, Rabbit, Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGEF antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SGEF Antibody

Binding Specificity: N-Term

Purpose: ARHGEF26 Antibody - N-terminal region

Sequence: MDGESEVDFS SNSITPLWRR RSIPQPHQVL GRSKPRPQSY QSPNGLLITD

Predicted Reactivity: Cow: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 90%

Characteristics: This is a rabbit polyclonal antibody against ARHGEF26. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SGEF

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55292-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SGEF

Target: SGEF (ARHGEF26) (rho Guanine Nucleotide Exchange Factor (GEF) 26 (ARHGEF26))

Alternative Name: ARHGEF26

Background:

Background Information: SGEF activates RhoG GTPase by promoting the exchange of GDP by GTP. SGEF is required for the formation of membrane ruffles during macropinocytosis. SGEF is also required for the formation of cup-like structures during trans-endothelial migration of leukocyte.

Gene Name: Rho guanine nucleotide exchange factor (GEF) 26

Alternative Symbols: SGEF, CSGEF, HMFN1864

Protein Name: Rho guanine nucleotide exchange factor 26

Molecular Weight: 97kDa

Gene ID: 26084

NCBI Accession: NP_056410

UniProt: Q96DR7