RRM1 antibody

Catalog No. ABIN7269988

This Rabbit Monoclonal antibody specifically detects RRM1 in WB. It exhibits reactivity toward Human.

Quick Overview for RRM1 antibody (ABIN7269988)

Target: RRM1 (Ribonucleotide Reductase M1 (RRM1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This RRM1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RRM1 Antibody

Purpose: RRM1 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human RRM1

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RRM1

Target: RRM1 (Ribonucleotide Reductase M1 (RRM1))

Alternative Name: RRM1

Background: This gene encodes the large and catalytic subunit of ribonucleotide reductase, an enzyme essential for the conversion of ribonucleotides into deoxyribonucleotides. A pool of available deoxyribonucleotides is important for DNA replication during S phase of the cell cycle as well as multiple DNA repair processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015],R1, RIR1, RR1,Epigenetics & Nuclear Signaling,RRM1

Molecular Weight: 90kDa

Gene ID: 6240

UniProt: P23921

Pathways: Positive Regulation of Endopeptidase Activity