RNF20 antibody

Catalog No. ABIN7270071

This anti-RNF20 antibody is a Rabbit Monoclonal antibody detecting RNF20 in WB. Suitable for Human.

Quick Overview for RNF20 antibody (ABIN7270071)

Target: RNF20 (Ring Finger Protein 20 (RNF20))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This RNF20 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RNF20 Antibody

Purpose: RNF20 Rabbit mAb

Cross-Reactivity: Human, Mouse

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human RNF20

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RNF20

Target: RNF20 (Ring Finger Protein 20 (RNF20))

Alternative Name: RNF20

Background: The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS). [provided by RefSeq, Feb 2012],BRE1, BRE1A, hBRE1,Cell Biology & Developmental Biology,Epigenetic writers and erasers of core Histones,Epigenetic writers and erasers of core Histones_Ubiquitination,Epigenetics & Nuclear Signaling,Histones,Ubiquitin,RNF20

Molecular Weight: 114kDa

Gene ID: 56254

UniProt: Q5VTR2