STK4 antibody (pThr387)

Catalog No. ABIN7270228

This Rabbit Polyclonal antibody specifically detects STK4 in WB. It exhibits reactivity toward Human.

Quick Overview for STK4 antibody (pThr387) (ABIN7270228)

Target: STK4 (serine/threonine Kinase 4 (STK4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STK4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-STK4 Antibody

Binding Specificity: pThr387

Purpose: Phospho-MST1/STK4-T387 Rabbit pAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Phosphorylated Antibodies

Purification: Affinity purification

Immunogen: A phospho specific peptide corresponding to residues surrounding T387 of human MST1/STK4.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for STK4

Target: STK4 (serine/threonine Kinase 4 (STK4))

Alternative Name: STK4

Background: The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process. [provided by RefSeq, Jul 2008],KRS2;MST1;YSK3;STK4,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Apoptosis,Autophagy,Hippo Signaling Pathway,Cardiovascular,Heart,Hypertrophy,Protein phosphorylation,STK4

Molecular Weight: 59kDa

Gene ID: 6789

UniProt: Q13043

Pathways: Tube Formation