STK4 antibody (AA 385-415)

Catalog No. ABIN3032542

This Rabbit Polyclonal antibody specifically detects STK4 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for STK4 antibody (AA 385-415) (ABIN3032542)

Target: STK4 (serine/threonine Kinase 4 (STK4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STK4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-STK4 Antibody

Binding Specificity: AA 385-415

Purpose: MST1 Antibody (Mammalian STE20-like protein kinase 1)

Cross-Reactivity (Details): Expected species reactivity: Bovine

Purification: Purified

Immunogen: A portion of amino acids 385-415 from the human protein was used as the immunogen for this MST1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the MST1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the MST1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for STK4

Target: STK4 (serine/threonine Kinase 4 (STK4))

Alternative Name: MST1 (Mammalian STE20-Like Protein Kinase 1)

Background: MST1 is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it is possible that this protein induces the chromatin condensation observed in this process.

UniProt: Q13043

Pathways: Tube Formation