SH3GLB1 antibody (AA 120-365)

Catalog No. ABIN7270280

The Rabbit Polyclonal anti-SH3GLB1 antibody has been validated for WB and IHC. It is suitable to detect SH3GLB1 in samples from Human.

Quick Overview for SH3GLB1 antibody (AA 120-365) (ABIN7270280)

Target: SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH3GLB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SH3GLB1 Antibody

Binding Specificity: AA 120-365

Purpose: Bif-1 Rabbit pAb

Sequence: KCGETQKRIG TADRELIQTS ALNFLTPLRN FIEGDYKTIA KERKLLQNKR LDLDAAKTRL KKAKAAETRN SSEQELRITQ SEFDRQAEIT RLLLEGISST HAHHLRCLND FVEAQMTYYA QCYQYMLDLQ KQLGSFPSNY LSNNNQTSVT PVPSVLPNAI GSSAMASTSG LVITSPSNLS DLKECSGSRK ARVLYDYDAA NSTELSLLAD EVITVFSVVG MDSDWLMGER GNQKGKVPIT YLELLN

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 120-365 of human Bif-1 (NP_057093.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SH3GLB1

Target: SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))

Alternative Name: SH3GLB1

Background: This gene encodes a SRC homology 3 domain-containing protein. The encoded protein interacts with the proapoptotic member of the Bcl-2 family, Bcl-2-associated X protein (Bax) and may be involved in regulating apoptotic signaling pathways. This protein may also be involved in maintaining mitochondrial morphology. Alternate splicing results in multiple transcript variants.,SH3GLB1,Bif-1,CGI-61,PPP1R70,dJ612B15.2,Cell Biology & Developmental Biology,Apoptosis,Autophagy,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,SH3GLB1

Molecular Weight: 29kDa/40kDa/43kDa

Gene ID: 51100

UniProt: Q9Y371

Pathways: Autophagy