STAU1/Staufen antibody

Catalog No. ABIN7270586

The Rabbit Monoclonal anti-STAU1/Staufen antibody is suitable to detect STAU1/Staufen in samples from Human. It has been validated for WB.

Quick Overview for STAU1/Staufen antibody (ABIN7270586)

Target: STAU1/Staufen (STAU1) (Staufen Double-Stranded RNA Binding Protein 1 (STAU1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This STAU1/Staufen antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-STAU1/Staufen Antibody

Purpose: Staufen Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Staufen

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for STAU1/Staufen

Target: STAU1/Staufen (STAU1) (Staufen Double-Stranded RNA Binding Protein 1 (STAU1))

Alternative Name: STAU1

Background: Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR. [provided by RefSeq, Jul 2008],PPP1R150, STAU,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Microtubules,Neuroscience,Signal Transduction,STAU1

Molecular Weight: 55kDa

Gene ID: 6780

UniProt: O95793

Pathways: Asymmetric Protein Localization