SMC3 antibody

Catalog No. ABIN7270616

The Rabbit Monoclonal anti-SMC3 antibody is suitable to detect SMC3 in samples from Human. It has been validated for WB, IP and IF.

Quick Overview for SMC3 antibody (ABIN7270616)

Target: SMC3 (Structural Maintenance of Chromosomes 3 (SMC3))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SMC3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)

Product Details anti-SMC3 Antibody

Purpose: SMC3 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human SMC3

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SMC3

Target: SMC3 (Structural Maintenance of Chromosomes 3 (SMC3))

Alternative Name: SMC3

Background: This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. [provided by RefSeq, Jul 2008],BAM, BMH, CDLS3, CSPG6, HCAP, SMC3L1,Apoptosis,Cancer,Cell Biology & Developmental Biology,Cell Cycle,DNA Damage & Repair,Epigenetics & Nuclear Signaling,SMC3

Molecular Weight: 141kDa

Gene ID: 9126

UniProt: Q9UQE7

Pathways: Stem Cell Maintenance