This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target
SAE1
(SUMO1 Activating Enzyme Subunit 1 (SAE1))
Alternative Name
SAE1
Background
Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1, MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010],AOS1, HSPC140, SUA1, UBLE1A,Cell Biology & Developmental Biology,Ubiquitin,Ubiquitin_Ubiquitin-Proteasome Signaling Pathway,SAE1