TLR7 antibody

Catalog No. ABIN7270848

This anti-TLR7 antibody is a Rabbit Monoclonal antibody detecting TLR7 in WB. Suitable for Human.

Quick Overview for TLR7 antibody (ABIN7270848)

Target: TLR7 (Toll-Like Receptor 7 (TLR7))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This TLR7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TLR7 Antibody

Purpose: TLR7 Rabbit mAb

Cross-Reactivity: Human

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human TLR7

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TLR7

Target: TLR7 (Toll-Like Receptor 7 (TLR7))

Alternative Name: TLR7

Background: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X. [provided by RefSeq, Jul 2008],TLR7,TLR7-like,Cell Intrinsic Innate Immunity Signaling Pathway,Epigenetics & Nuclear Signaling,Immunology & Inflammation,Innate Immunity_TLR Signaling,NF-kB Signaling Pathway,Signal Transduction,Toll-like Receptor Signaling Pathway,TLR7

Molecular Weight: 140kDa

Gene ID: 51284

UniProt: Q9NYK1

Pathways: TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades