TLR9 antibody (AA 350-450)

Catalog No. ABIN7270849

This Rabbit Polyclonal antibody specifically detects TLR9 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for TLR9 antibody (AA 350-450) (ABIN7270849)

Target: TLR9 (Toll-Like Receptor 9 (TLR9))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR9 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TLR9 Antibody

Binding Specificity: AA 350-450

Purpose: TLR9 Rabbit pAb

Sequence: SFAHLSLAPS FGSLVALKEL DMHGIFFRSL DETTLRPLAR LPMLQTLRLQ MNFINQAQLG IFRAFPGLRY VDLSDNRISG ASELTATMGE ADGGEKVWLQ P

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 350-450 of human TLR9 (NP_059138.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TLR9

Target: TLR9 (Toll-Like Receptor 9 (TLR9))

Alternative Name: TLR9

Background: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.,TLR9,CD289,Signal Transduction,Immunology & Inflammation,CD markers,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,TLR9

Molecular Weight: 109kDa/114kDa/115kDa/118kDa

Gene ID: 54106

UniProt: Q9NR96

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades