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TLK1 antibody (AA 160-230)

The Rabbit Polyclonal anti-TLK1 antibody has been validated for WB and IHC. It is suitable to detect TLK1 in samples from Human.
Catalog No. ABIN7270859

Quick Overview for TLK1 antibody (AA 160-230) (ABIN7270859)

Target

See all TLK1 Antibodies
TLK1 (Tousled-Like Kinase 1 (TLK1))

Reactivity

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Human

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This TLK1 antibody is un-conjugated

Application

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Western Blotting (WB), Immunohistochemistry (IHC)
  • Binding Specificity

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    AA 160-230

    Purpose

    TLK1 Rabbit pAb

    Sequence

    PVRGIPPAIR SPQNSHSHST PSSSVRPNSP SPTALAFGDH PIVQPKQLSF KIIQTDLTML KLAALESNKI Q

    Cross-Reactivity

    Human, Mouse, Rat

    Characteristics

    Polyclonal Antibodies

    Purification

    Affinity purification

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 160-230 of human TLK1 (NP_036422.3).

    Isotype

    IgG
  • Application Notes

    WB,1:500 - 1:2000,IHC,1:50 - 1:100

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    TLK1 (Tousled-Like Kinase 1 (TLK1))

    Alternative Name

    TLK1

    Background

    The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene.,TLK1,PKU-beta,Epigenetics & Nuclear Signaling,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Apoptosis,TLK1

    Molecular Weight

    63kDa/77kDa/81kDa/86kDa/89kDa

    Gene ID

    9874

    UniProt

    Q9UKI8
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