TFE3 antibody (AA 1-160)

Catalog No. ABIN7270893

This anti-TFE3 antibody is a Rabbit Polyclonal antibody detecting TFE3 in IF. Suitable for Human.

Quick Overview for TFE3 antibody (AA 1-160) (ABIN7270893)

Target: TFE3 (Transcription Factor E3 (TFE3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFE3 antibody is un-conjugated

Application: Immunofluorescence (IF)

Product Details anti-TFE3 Antibody

Binding Specificity: AA 1-160

Purpose: TFE3 Rabbit pAb

Sequence: MSHAAEPARD GVEASAEGPR AVFVLLEERR PADSAQLLSL NSLLPESGIV ADIELENVLD PDSFYELKSQ PLPLRSSLPI SLQATPATPA TLSASSSAGG SRTPAMSSSS SSRVLLRQQL MRAQAQEQER RERREQAAAA PFPSPAPASP AISVVGVSAG

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human TFE3 (NP_006512.2).

Isotype: IgG

Application Details

Application Notes: IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TFE3

Target: TFE3 (Transcription Factor E3 (TFE3))

Alternative Name: TFE3

Background: This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants.,TFE3,RCCP2,RCCX1,TFEA,bHLHe33,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Immunology & Inflammation,TFE3

Molecular Weight: 11kDa/61kDa

Gene ID: 7030

UniProt: P19532