TADA3L antibody (AA 270-369)

Catalog No. ABIN7270900

This Rabbit Polyclonal antibody specifically detects TADA3L in WB and IF. It exhibits reactivity toward Human.

Quick Overview for TADA3L antibody (AA 270-369) (ABIN7270900)

Target: TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TADA3L antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-TADA3L Antibody

Binding Specificity: AA 270-369

Purpose: TADA3 Rabbit pAb

Sequence: EENIISPMED SPIPDMSGKE SGADGASTSP RNQNKPFSVP HTKSLESRIK EELIAQGLLE SEDRPAEDSE DEVLAELRKR QAELKALSAH NRTKKHDLLR

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 270-369 of human TADA3 (NP_597814.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TADA3L

Target: TADA3L (TADA3) (Transcriptional Adaptor 3 (TADA3))

Alternative Name: TADA3

Background: DNA-binding transcriptional activator proteins increase the rate of transcription by interacting with the transcriptional machinery bound to the basal promoter in conjunction with adaptor proteins, possibly by acetylation and destabilization of nucleosomes. The protein encoded by this gene is a transcriptional activator adaptor and a component of the histone acetyl transferase (HAT) coactivator complex which plays a crucial role in chromatin modulation and cell cycle progression. Along with the other components of the complex, this protein links transcriptional activators bound to specific promoters, to histone acetylation and the transcriptional machinery. The protein is also involved in the stabilization and activation of the p53 tumor suppressor protein that plays a role in the cellular response to DNA damage. Alternate splicing results in multiple transcript variants of this gene.,TADA3,ADA3,NGG1,STAF54,TADA3L,hADA3,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Apoptosis,TADA3

Molecular Weight: 41kDa/48kDa

Gene ID: 10474

UniProt: O75528

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway