TRIM62 antibody (AA 120-280)
Quick Overview for TRIM62 antibody (AA 120-280) (ABIN7270996)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 120-280
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Purpose
- TRIM62 Rabbit pAb
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Sequence
- HEQHQVTGID DAFDELQREL KDQLQALQDS EREHTEALQL LKRQLAETKS STKSLRTTIG EAFERLHRLL RERQKAMLEE LEADTARTLT DIEQKVQRYS QQLRKVQEGA QILQERLAET DRHTFLAGVA SLSERLKGKI HETNLTYEDF PTSKYTGPLQ Y
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 120-280 of human TRIM62 (NP_060677.2).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- TRIM62 (Tripartite Motif Containing 62 (TRIM62))
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Alternative Name
- TRIM62
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Background
- E3 ubiquitin ligase that plays a role in antifungal immunity by mediating 'Lys-27'-linked ubiquitination of CARD9 downstream of C-type lectin receptors, leading to CARD9 activation, followed by activation of NF-kappa-B and MAP kinase p38 pathways. E3 ubiquitin ligase activity is dependent on E2 ubiquitin-conjugating enzyme UBE2D2.,TRIM62,DEAR1,Cell Biology & Developmental Biology,TRIM62
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Molecular Weight
- 40kDa/54kDa
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Gene ID
- 55223
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UniProt
- Q9BVG3
Target
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