UQCRH antibody

Catalog No. ABIN7271126

The Rabbit Monoclonal anti-UQCRH antibody has been validated for WB and IHC. It is suitable to detect UQCRH in samples from Human.

Quick Overview for UQCRH antibody (ABIN7271126)

Target: UQCRH (Uqcrh) (Ubiquinol-Cytochrome C Reductase Hinge Protein (Uqcrh))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This UQCRH antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-UQCRH Antibody

Purpose: UQCRH Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human UQCRH.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for UQCRH

Target: UQCRH (Uqcrh) (Ubiquinol-Cytochrome C Reductase Hinge Protein (Uqcrh))

Alternative Name: UQCRH

Background: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII, ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII and cytochrome c oxidase (complex IV, CIV, that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.,UQCRH

Molecular Weight: 11kDa

Gene ID: 7388

UniProt: P07919