UGT1A6 antibody (AA 65-270)

Catalog No. ABIN7271193

This anti-UGT1A6 antibody is a Rabbit Polyclonal antibody detecting UGT1A6 in WB and IF. Suitable for Human.

Quick Overview for UGT1A6 antibody (AA 65-270) (ABIN7271193)

Target: UGT1A6 (UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UGT1A6 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-UGT1A6 Antibody

Binding Specificity: AA 65-270

Purpose: UGT1A6 Rabbit pAb

Sequence: LLLKESKYYT RKIYPVPYDQ EELKNRYQSF GNNHFAERSF LTAPQTEYRN NMIVIGLYFI NCQSLLQDRD TLNFFKESKF DALFTDPALP CGVILAEYLG LPSVYLFRGF PCSLEHTFSR SPDPVSYIPR CYTKFSDHMT FSQRVANFLV NLLEPYLFYC LFSKYEELAS AVLKRDVDII TLYQKVSVWL LRYDFVLEYP RPVMPN

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 65-270 of human UGT1A6 (NP_001063.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for UGT1A6

Target: UGT1A6 (UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6))

Alternative Name: UGT1A6

Background: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants.,UGT1A6;GNT1;HLUGP;HLUGP1;UDPGT;UDPGT 1-6;UGT1;UGT1A6S;UGT1F;UDPGT1-6,Cancer,Signal Transduction,Endocrine & Metabolism,Drug metabolism,UGT1A6

Molecular Weight: 29kDa/50kDa/60kDa

Gene ID: 54578

UniProt: P19224

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha