VAV3 antibody

Catalog No. ABIN7271305

This Rabbit Monoclonal antibody specifically detects VAV3 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for VAV3 antibody (ABIN7271305)

Target: VAV3 (Vav 3 Oncogene (VAV3))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This VAV3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-VAV3 Antibody

Purpose: VAV3 Rabbit mAb

Cross-Reactivity: Human, Mouse

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human VAV3

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for VAV3

Target: VAV3 (Vav 3 Oncogene (VAV3))

Alternative Name: VAV3

Background: This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],B Cell Receptor Signaling Pathway,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Cytoskeleton,Cytoskeleton_Actins,G protein signaling,G protein signaling_Small G proteins,Immunology & Inflammation,Signal Transduction,T Cell Receptor Signaling Pathway,VAV3

Molecular Weight: 98kDa

Gene ID: 10451

UniProt: Q9UKW4

Pathways: Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway