YAP1 antibody (pSer128)

Catalog No. ABIN7271416

This Rabbit Polyclonal antibody specifically detects YAP1 in WB. It exhibits reactivity toward Human.

Quick Overview for YAP1 antibody (pSer128) (ABIN7271416)

Target: YAP1 (Yes-Associated Protein 1 (YAP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YAP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-YAP1 Antibody

Binding Specificity: pSer128

Purpose: Phospho-YAP1-S128 Rabbit pAb

Cross-Reactivity: Human, Mouse

Characteristics: Phosphorylated Antibodies

Purification: Affinity purification

Immunogen: A synthetic phosphorylated peptide around S128 of human YAP1 (NP_001123617.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for YAP1

Target: YAP1 (Yes-Associated Protein 1 (YAP1))

Alternative Name: YAP1

Background: This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.,COB1,YAP,YAP2,YAP65,YKI,YAP1,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Hippo Signaling Pathway,Protein phosphorylation,YAP1

Molecular Weight: 36kDa/48kDa/49kDa/50kDa/52kDa/53kDa/54kDa

Gene ID: 10413

UniProt: P46937

Pathways: MAPK Signaling, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha