YAP1 antibody (pSer397)

Catalog No. ABIN7271417

The Rabbit Polyclonal anti-YAP1 antibody has been validated for WB. It is suitable to detect YAP1 in samples from Human.

Quick Overview for YAP1 antibody (pSer397) (ABIN7271417)

Target: YAP1 (Yes-Associated Protein 1 (YAP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YAP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-YAP1 Antibody

Binding Specificity: pSer397

Purpose: phospho-YAP1-S397 Rabbit pAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Phosphorylated Antibodies

Purification: Affinity purification

Immunogen: A phospho specific peptide corresponding to residues surrounding S397 of human YAP1.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for YAP1

Target: YAP1 (Yes-Associated Protein 1 (YAP1))

Alternative Name: YAP1

Background: This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013],COB1,YAP,YAP2,YAP65,YKI,YAP1,Cancer,Cell Biology & Developmental Biology,Epigenetics & Nuclear Signaling,Hippo Signaling Pathway,Kinase,Kinase_Tyrosine kinases,Protein phosphorylation,Signal Transduction,Transcription Factors,YAP1

Molecular Weight: 36kDa/48kDa/49kDa/50kDa/52kDa/53kDa/54kDa

Gene ID: 10413

UniProt: P46937

Pathways: MAPK Signaling, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha