ZFX antibody (AA 180-380)

Catalog No. ABIN7271539

This Rabbit Polyclonal antibody specifically detects ZFX in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for ZFX antibody (AA 180-380) (ABIN7271539)

Target: ZFX (Zinc Finger Protein, X-Linked (ZFX))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZFX antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ZFX Antibody

Binding Specificity: AA 180-380

Purpose: ZFX Rabbit pAb

Sequence: VLVADCASEA VIDANGIPVD QQDDDKGNCE DYLMISLDDA GKIEHDGSSG MTMDTESEID PCKVDGTCPE VIKVYIFKAD PGEDDLGGTV DIVESEPEND HGVELLDQNS SIRVPREKMV YMTVNDSQPE DEDLNVAEIA DEVYMEVIVG EEDAAAAAAA AAVHEQQMDD NEIKTFMPIA WAAAYGNNSD GIENRNGTAS A

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 180-380 of human ZFX (NP_003401.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ZFX

Target: ZFX (Zinc Finger Protein, X-Linked (ZFX))

Alternative Name: ZFX

Background: This gene on the X chromosome is structurally similar to a related gene on the Y chromosome. It encodes a member of the krueppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers. Studies in mouse embryonic and adult hematopoietic stem cells showed that this gene was required as a transcriptional regulator for self-renewal of both stem cell types, but it was dispensable for growth and differentiation of their progeny. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, but the full-length nature of some variants has not been determined.,ZFX,ZNF926,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Stem Cells,Embryonic Stem Cells,Hematopoietic Progenitors,ZFX

Molecular Weight: 66kDa/90kDa/94kDa

Gene ID: 7543

UniProt: P17010