ZGPAT antibody (AA 212-511)

Catalog No. ABIN7271544

This anti-ZGPAT antibody is a Rabbit Polyclonal antibody detecting ZGPAT in WB. Suitable for Human.

Quick Overview for ZGPAT antibody (AA 212-511) (ABIN7271544)

Target: ZGPAT (Zinc Finger, CCCH-Type with G Patch Domain (ZGPAT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZGPAT antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ZGPAT Antibody

Binding Specificity: AA 212-511

Purpose: ZGPAT Rabbit pAb

Sequence: DPDLSSLQAG SACLAKHQDG LWHAARITDV DNGYYTVKFD SLLLREAVVE GDGILPPLRT EATESDSDSD GTGDSSYARV VGSDAVDSGT CSSAFAGWEV HTRGIGSRLL TKMGYEFGKG LGRHAEGRVE PIHAVVLPRG KSLDQCVETL QKQTRVGKAG TNKPPRCRGR GARPGGRPAP RNVFDFLNEK LQGQAPGALE AGAAPAGRRS KDMYHASKSA KRALSLRLFQ TEEKIERTQR DIRSIQEALA RNAGRHSVAS AQLQEKLAGA QRQLGQLRAQ EAGLQQEQRK ADTHKKMTEF

Cross-Reactivity: Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 212-511 of human ZGPAT (NP_852150.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ZGPAT

Target: ZGPAT (Zinc Finger, CCCH-Type with G Patch Domain (ZGPAT))

Alternative Name: ZGPAT

Background: Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis.,ZGPAT,GPATC6,GPATCH6,KIAA1847,ZC3H9,ZC3HDC9,ZIP,Epigenetics & Nuclear Signaling,Transcription Factors,ZGPAT

Molecular Weight: 20kDa/54kDa/55kDa/57kDa

Gene ID: 84619

UniProt: Q8N5A5

Pathways: EGFR Signaling Pathway