The Human Monoclonal anti-SARS-CoV-2 Spike S2 antibody has been validated for . It is suitable to detect SARS-CoV-2 Spike S2 in samples from SARS Coronavirus-2 (SARS-CoV-2).
Catalog No. ABIN7271738
Quick Overview for Recombinant SARS-CoV-2 Spike S2 antibody (ABIN7271738)
Anti-SARS-CoV-2 Spike S2 protein Antibody, Human IgG4 (AS86)
Specificity
This product is a specific antibody against SARS-CoV-2 Spike S2 protein. Cross-reactivity with S2 protein of other coronaviruses has not been tested.
Characteristics
Recombinant Antibodies produced in CHO. Anti-SARS-CoV-2 Spike S2 protein Antibody, Human IgG4 (AS86) is isolated from a SARS-CoV-2 infected patient and is recombinantly produced from CHO cells.
Immunogen
Anti-SARS-CoV-2 Spike S2 protein Antibody, Human IgG4 (AS86) is isolated from a SARS-CoV-2 infected patient and is recombinantly produced from CHO cells.
It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.