CD16 antibody

Catalog No. ABIN7271861

The Mouse Monoclonal anti-CD16 antibody has been validated for FACS. It is suitable to detect CD16 in samples from Human, Rhesus Monkey, Cynomolgus and Baboon.

Quick Overview for CD16 antibody (ABIN7271861)

Target: CD16

Reactivity: Human, Rhesus Monkey, Cynomolgus, Baboon

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD16 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Grade: GMP Grade

Clone: C-4H1G

Product Details anti-CD16 Antibody

Purpose: CD16 Unconjugated Antibody

Characteristics: Alternative clone name HuNK2, the clone C-4H1G, a mouse monoclonal antibody binds to the 50-65 kDa transmembrane protein of IgG FcγRIII known as CD16, a surface antigen commonly associated with human NK cells. In addition to surface expression on NK cells, CD16 is expressed on activated monocytes, macrophages, neutrophils, and placental trophoblasts in humans. C-4H1G has been showed to inhibit the binding of immune complex to NK cells, inhibit cytotoxicity of NK cells, and induce calcium fluxes in NK cells and neutrophils.

Purification: Purified

Purity: >95 %

Immunogen: Human peripheral blood T lymphocytes from a NK-leukemia patient

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for CD16

Target: CD16

Alternative Name: CD16

Gene ID: 2214

UniProt: Q92835

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process