CHML antibody (C-Term)

Catalog No. ABIN7272972

The Goat Polyclonal anti-CHML antibody is suitable to detect CHML in samples from Human, Mouse, Rat, Monkey, Sheep, Rabbit, Pig, Horse, Hamster, Guinea Pig, Goat, Donkey, Dog, Cow, Chicken, Cat and Avian. It has been validated for WB.

Quick Overview for CHML antibody (C-Term) (ABIN7272972)

Target: CHML (Choroideremia-Like (Rab Escort Protein 2) (CHML))

Reactivity: Human, Mouse, Rat, Monkey, Sheep, Rabbit, Pig, Horse, Hamster, Guinea Pig, Goat, Donkey, Dog, Cow, Chicken, Cat, Avian

Host: Goat

Clonality: Polyclonal

Conjugate: This CHML antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHML Antibody

Binding Specificity: C-Term

Purpose: Anti-REP2

Sequence: IIFDGDDKQP EAPGTNNVVM AKLESSEESK NLESPEKHLQ N

Specificity: Detects endogenous REP2 by Western blot. This Ab is specific for REP2, it does not cross-react with REP1.

Cross-Reactivity (Details): Human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other

Characteristics: Choroideremia (Rab escort protein 2)

Purification: Epitope affinity purified

Immunogen: Purified recombinant peptide derived from within residues 617 aa - stop at the C-terminus of human REP2 produced in E. coli.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:5,000

Restrictions: For Research Use only

Handling

Concentration: 3 mg/mL

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: The antibody solution should be gently mixed before use.

Storage: 4 °C,-20 °C

Storage Comment: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Target Details for CHML

Target: CHML (Choroideremia-Like (Rab Escort Protein 2) (CHML))

Alternative Name: REP2

Background:

REP2 is the component A2 of the RAB geranylgeranyl transferase holoenzyme. REP2 binds most of unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction and may substitute REP1.

CHML, CHM like, rab escort protein 2 antibody.