Adenosine A2a Receptor antibody (C-Term)

Catalog No. ABIN7272985

The Goat Polyclonal anti-Adenosine A2a Receptor antibody (ABIN7272985) specifically detects Adenosine A2a Receptor in WB, IHC (p) and IHC (fro). The antibody is reactive with Human, Mouse, Rat, Dog and Monkey samples.

Quick Overview for Adenosine A2a Receptor antibody (C-Term) (ABIN7272985)

Target: Adenosine A2a Receptor (ADORA2A)

Reactivity: Human, Mouse, Rat, Dog, Monkey

Host: Goat

Clonality: Polyclonal

Conjugate: This Adenosine A2a Receptor antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Adenosine A2a Receptor Antibody

Binding Specificity: C-Term

Purpose: Anti-ADORA2A

Sequence: YALGLVSGGS AQESQGNTGL PDVELLSHEL KGVCPEPPGL DDPLAQDGAG VS

Specificity: Detects endogenous levels of ADORA2A in brain by Western blot.

Cross-Reactivity (Details): Reacts against human, rat, mouse, canine and monkey proteins.

Characteristics: Adenosine receptor A2a

Purification: Epitope affinity purified

Immunogen: Recombinant peptide derived from within residues 360 aa to the C-terminus of human ADORA2A produced in E. coli.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:2,000, IHC-P:1:250-1:1,000, IHC-F:1:250-1:1,000

Restrictions: For Research Use only

Handling

Concentration: 3 mg/mL

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: The antibody solution should be gently mixed before use.

Storage: 4 °C,-20 °C

Storage Comment: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Target Details for Adenosine A2a Receptor

Target: Adenosine A2a Receptor (ADORA2A)

Alternative Name: ADORA2A

Background:

Goat polyclonal antibody to ADORA2A. It is a member of the guanine nucleotide binding coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular stimuli and activate intracellular signal transduction pathways. It plays an important role in many biological functions, including cerebral and renal blood flow, immune function, cardiac rhythm and circulation, pain regulation, and sleep. It has been implicated in pathophysiological conditions such as neurodegenerative and inflammatory disorders.

A2aR, ADORA2, RDC8 antibody.

Pathways: Neurotrophin Signaling Pathway, cAMP Metabolic Process, Synaptic Membrane, Feeding Behaviour, Cancer Immune Checkpoints