SARS-CoV-2 Spike antibody (RBD)

Catalog No. ABIN7272992

This Goat Polyclonal antibody specifically detects SARS-CoV-2 Spike in WB. It exhibits reactivity toward SARS Coronavirus-2 (SARS-CoV-2).

Quick Overview for SARS-CoV-2 Spike antibody (RBD) (ABIN7272992)

Target: SARS-CoV-2 Spike (SARS-CoV-2 S)

Reactivity: SARS Coronavirus-2 (SARS-CoV-2)

Host: Goat

Clonality: Polyclonal

Conjugate: This SARS-CoV-2 Spike antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SARS-CoV-2 Spike Antibody

Binding Specificity: RBD

Purpose: anti-Spike RBD Domain (SARS-CoV-2)

Sequence: NATRFASVYA WNRKRISNCV ADYSVLYNSA SFSTFKCYGV SPTKLNDLCF TNVYADSF

Specificity: In lysates of transfected cells with the plasmid containing the sequence used, detects the fusion protein by Western blot.

Cross-Reactivity (Details): Reacts with SARS-CoV-2 protein

Purification: Epitope affinity purified

Immunogen: Affinity purified recombinant fusion protein using the spike protein RBD domain (residues 320 to 420) and produced in E. coli.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:2,000

Restrictions: For Research Use only

Handling

Concentration: 3 mg/mL

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: The antibody solution should be gently mixed before use.

Storage: 4 °C,-20 °C

Storage Comment: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Target Details for SARS-CoV-2 Spike

Target: SARS-CoV-2 Spike (SARS-CoV-2 S)

Alternative Name: Spike (SARS-CoV-2)

Target Type: Viral Protein

Background:

The spike or S glycoprotein is a transmembrane protein with a molecular weight of about 150 kDa found in the outer portion of the SARS-CoV-2 virus. This protein is composed of two subunits, S1 and S2 and plays a key role in the receptor recognition and cell membrane fusion process. The S1 subunit contains a receptor-binding domain that recognizes and binds to the host receptor angiotensin-converting enzyme 2, while the S2 subunit mediates viral cell membrane fusion.

S glycoprotein SARS Coronavirus-2, Spike RBD Domain SARS Coronavirus-2 antibody.

Molecular Weight: 150 kDa