MERS-CoV Nucleocapsid antibody

Catalog No. ABIN7383848

This Mouse Monoclonal antibody specifically detects MERS-CoV Nucleocapsid in ELISA and WB. It exhibits reactivity toward Middle East Respiratory Syndrome Coronavirus (MERS-CoV).

Quick Overview for MERS-CoV Nucleocapsid antibody (ABIN7383848)

Target: MERS-CoV Nucleocapsid (MERS-CoV N) (MERS-Coronavirus Nucleocapsid Protein (MERS-CoV N))

Reactivity: Middle East Respiratory Syndrome Coronavirus (MERS-CoV)

Host: Mouse

Clonality: Monoclonal

Conjugate: This MERS-CoV Nucleocapsid antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Clone: 1E1

Product Details anti-MERS-CoV Nucleocapsid Antibody

Specificity: Anti-MERS-CoV Nucleocapsid Monoclonal Antibody

Purification: Protein A Affinity

Immunogen: Recombinant MERS-CoV Nucleoprotein / NP protein (His Tag), ABIN7198809

Isotype: IgG1

Application Details

Application Notes: WB 1:1000-1:5000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 0.2 μm filtered solution in PBS

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MERS-CoV Nucleocapsid

Target: MERS-CoV Nucleocapsid (MERS-CoV N) (MERS-Coronavirus Nucleocapsid Protein (MERS-CoV N))

Alternative Name: MERS-CoV Nucleocapsid

Background: Coronavirus NP,coronavirus Nucleocapsid,coronavirus Nucleoprotein,cov np,ncov NP,novel coronavirus Nucleoprotein,NP,Nucleocapsid,Nucleoprotein,Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.